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The Pf80S emetine structure reveals an edge centered on the ethyl group of the molecule that could be subjected to modification to increase the affinity of emetine for the binding pocket.
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This result is significant as ANO1 could be subjected to modifications that are not reproduced in the overexpressing cell clones.
Only the volume enclosed by the two intake port arms was subjected to modification.
The optimized formula was subjected to modification by addition of different proteoglycans, as a compensatory treatment, to improve its pharmacological properties.
The comparison of ZAP-70 and Syk mRNA levels between normal and leukaemic peripheral whole blood showed that the expression ratio ZAP-70/Syk is subjected to modification depending on the leukaemia status of patients.
This prompted us to examine whether PHB is subjected to modification by OGT.
The folded ERRE RNA alone or preformed ERev-ERRE complexes were subjected to modification by each chemical reagent.
They are subjected to modification steps similar to those of their yeast counterpart.
Granulated PE was melted for 3 min and pressed under 100 atm at 180°C to obtain plates which were subjected to modification with the silanes (Table 1).
The technology of construction is subjected to modifications to overcome the ever changing transport pattern, materials for the building and sub-grade environments.
The newly synthesized chondroitin chain is subjected to modifications, such as epimerization and sulfation.
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