Sentence examples for be stringently regulated to from inspiring English sources

However, the recombination process must be stringently regulated to prevent formation of chromosomal translocations, which can lead to tumors.

The developmental reprogramming, the production of virulence factors and the increased stress of embarking on a pathogenic interaction are stringently regulated to reduce the metabolic burden on a pathogen.

However, since sustained PERK activation could be harmful [57] and persistent ER stress attenuates survival pathways mediated by IRE1 and ATF6 signaling [19], this may explain why GRP78va expression might be stringently regulated at the transcript stability level, as well as at the post-translational level.

For this reason, the discharge of industrial effluents containing Cu II) must be stringently regulated in order to reduce environmental pollution.

As a central regulator of bacterial conjugation, the intracellular level of TraJ is stringently regulated at multiple levels by different host and plasmid-encoded factors.

In addition, negative regulators may also be important factors to be taken into consideration in this analysis because the cell responses must be stringently regulated.

In T. parva, a massively parallel signature sequencing (MPSS) study indicates that the majority of genes are transcriptionally active in the schizont stage, but their transcription may not be stringently regulated and, instead, vary stochastically between different host cells or time points.

These data are consistent with the in vitro observations that cyclin D1 can be stringently regulated as a function of subcellular localisation (Alt et al, 2000; Radu et al, 2003) and reveal that distinct localisation patterns are observed in prostate cancer.

A further complication is that in vivo substrate supply to the respiratory chain is stringently regulated by factors such as dietary and hormonal status, leading to alterations in the steady-state reduction potential of mitochondrial electron carriers.

Student halls should be signed up to one of the National Codes of Management, which are stringently regulated.

The number and subunit compositions of synaptic AMPARs are stringently regulated because activity dependent changes in functional postsynaptic AMPARs contribute to the two main forms of synaptic plasticity that are believed to underlie learning and memory in the hippocampus [1], [2].