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However, since sustained PERK activation could be harmful [57] and persistent ER stress attenuates survival pathways mediated by IRE1 and ATF6 signaling [19], this may explain why GRP78va expression might be stringently regulated at the transcript stability level, as well as at the post-translational level.
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As a central regulator of bacterial conjugation, the intracellular level of TraJ is stringently regulated at multiple levels by different host and plasmid-encoded factors.
However, the recombination process must be stringently regulated to prevent formation of chromosomal translocations, which can lead to tumors.
For this reason, the discharge of industrial effluents containing Cu II) must be stringently regulated in order to reduce environmental pollution.
In addition, negative regulators may also be important factors to be taken into consideration in this analysis because the cell responses must be stringently regulated.
The basolateral membrane arises from the adaptor protein (AP -enriched domAP -enriched sorting is stringently regulatedomainignand at the cytoplasmitstail, AP and sortingd proteisstringentlyg clathregulated
Indeed, FabI is stringently regulated within the fatty acid biosynthesis pathway [ 32], and de-regulation inhibits cell growth and viability [ 44, 45].
Regulation of the T6SS in P. aeruginosa is complex; the system is stringently regulated post-transcriptionally by the Gac/Rsm pathway and post-translationally by threonine phosphorylation [3], [16], [30].
Student halls should be signed up to one of the National Codes of Management, which are stringently regulated.
Because unlike doctors, who can be overworked with relative impunity (and that's even before Mr Hunt's new contract waters down what little protections we have), pilots' hours are stringently regulated.
Oil concentration levels in municipal waste water effluent streams are stringently regulated in most parts of the world.
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CEO of Professional Science Editing for Scientists @ prosciediting.com