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The inflammatory and tissue-regenerating roles of HMGB1 may be strictly interconnected, and are discussed here.
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In particular, increasing evidence has shown that aggregation of amyloid beta (Aβ), glycogen synthase kinase 3β (GSK-3β) and oxidative stress are strictly interconnected and their concomitant modulation may have a positive and synergic effect in contrasting AD-related impairments.
The germinal component (spermatogonia, primary and secondary spermatocytes, round spermatids, and elongating/elongated spermatids) is strictly interconnected with the somatic component, the Sertoli cells, which sustains spermatogenesis giving structural support and nourishment to germ cells [ 5, 6].
Ganglioside profile and metabolism is strictly interconnected with melanoma aggressiveness.
All the factors significantly associated with prolonged viral shedding, i.e. presence of any complication, pneumonia and duration of antiviral administration (Table 2), are strictly interconnected, suggesting that the deciding factor for prolonged shedding is, in fact, the presence of pneumonia.
Moreover, these aspects are strictly interconnected with one another.
Viseguy is strictly cloak-and-dagger.
Many government activities are interconnected and cannot be isolated.
They have to be interconnected and turning in opposite directions.
These challenges are interconnected, and they are urgent.
Arabs are increasingly interconnected and plugged in.
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CEO of Professional Science Editing for Scientists @ prosciediting.com