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Owing to these technical failures of system integration, treatment had to be stopped ahead of schedule in three patients.
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Hormone use has dropped sharply since July 2002, when a large study in the United States called the Women's Health Initiative was stopped ahead of schedule because it detected an increased risk of breast cancer in women who took Prempro, a widely used hormone combination.
Researchers had also once thought hormones might prevent heart attacks and strokes, but the latest findings -- from the Women's Health Initiative, a large federal study of the combination therapy that was stopped ahead of schedule a year ago because the hormones caused a small but significant increase in the risk of breast cancer -- also found that hormones increased those risks.
Although full results are not known, Celgene announced in its second-quarter earnings release Thursday that the study had been stopped ahead of schedule because the difference between patients getting Revlimid and those on a control group was already apparent.
I had just come through an intersection, and a school bus was stopped ahead.
After 535 patients had been accrued, recruitment was stopped ahead of schedule for low accrual rates.
This study was stopped ahead of schedule and unblinded after independent data monitoring committee found significant survival superiority in nivolumab over dacarbazine.
In that case, Mr. Wells said, the test probably would be stopped well ahead of schedule, valves would be reopened and collection systems that had been shut down for the test would start again.
Lawson recalls: "[Wall Street] lobbied Alan Greenspan and got him to make representations to the Bank of England that I should be stopped from going ahead.
The fight had to be stopped, even though Klitschko was ahead on points.
When it was stopped, Ali was ahead on the scorecards of the referee and two judges.
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