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It may be speculated whether a read-through of transcription across convergent genes is the basis of this regulation.
It may be speculated whether a proportion of these patients have a more resistant disease (i.e. less fluctuations of DTCs despite chemotherapy).
At present, it can therefore only be speculated whether a blood test with faecal occult blood test (FOBT -like perFOBT -likeould performanceilar reductions in incidence and mortality to those seen in previous randomised FOBT trials.
In reality, however, alcoholism is far more prevalent in the Swedish citizenry and it could be speculated whether a truer representation (better detection) of substance use problems in the cohort would alter the findings and, if so, in what direction.
It may be speculated whether a food resource targeted to an individual with malnutrition is more prone to be regarded as a resource for the family and thus to conflicting views on its usage in comparisons to medicines obtained for treatment of individuals with a medical condition.
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It is not within the scope of our study to give a comprehensive explanation for this finding, but it can be speculated whether this reflects a pro-inflammatory situation or a concomitant infectious disease that impairs the protective mucosal barrier and could thus promote a more effective adherence of the pathogen.
It could be speculated whether this was a tissue response in order to balance the overall energetic status, a notion supported from reduced hepatic beta-oxidation in the same fish [ 19].
It can be speculated whether this was a paradoxical response leading to acute lung injury.
Furthermore, it can be speculated, whether HEPACAM2 plays a different role in malignancy and metastasis of canine mammary tumours since its transcriptional levels are different in carcinomas and their lymph node metastases when compared to HEPACAM1.
The very small number of animals represented in these studies means that it can only be speculated whether such changes reflect a degree of natural variation in the donor animals, or whether there are as yet unrecognised influences from recipient host factors.
It can be speculated whether the lack of an atherosclerotic phenotype may be explained by model-associated specificities: the NAD+-dependence of sirtuins, confining their maximal activity to times of energy deprivation, may interfere with the atherogenic high-cholesterol diet applied in this study; i.e., Sirt3 activity in the control group may have been decreased by this high-caloric diet.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com