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Hence, it could be speculated that tumours with higher cell density and/or mitochondria would enhance more markedly on MEMRI.
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It is speculated that tumours escape hormonal control via reduction in corepressor proteins.
In conclusion, it may be speculated that the suggested tumour suppressive function of CAR is at least in part mediated by regulating the α-catenin expression.
It could be speculated that in the Runx2 or Runx3 overexpressing tumours, other factors might exert stronger tumour promoting effects, and thereby mask the tumour suppressive effects of Runx2 or Runx3.
It can be speculated that the other surrogate markers of tumour angiogenesis or other biological variables for haematogenous dissemination or the growth pathways in relation to ER-negative status contribute to the worse survival of British patients.
Based on the connection between HOXC8 and ON, it could be speculated that wound formation (including certain aspects of tumour formation) could be a trigger.
It can therefore be speculated that HEPACAM2 expression decreases with increasing malignancy of canine mammary tumours as is usually observed for cell-adhesion genes in a wide variety of tumours types.
It may be speculated that the response rate could be increased by selecting patients whose tumour expresses the VDR.
As all rectal tumour samples were taken from post-treatment surgical specimens, it could be speculated that SATB2 levels are modified by neoadjuvant RT or chemotherapy.
Interestingly, FasL expression was also observed in tumour cells of non-lymphoid origin and it was speculated that establishment of a tumour-associated immune privilege might enable malignantly transformed cells to evade immune surveillance and possibly also to selectively kill infiltrating lymphocytes [ 11].
In that study it was speculated that bleomycin after electroporation of tumours severely damages vasculature of the tumours and consequently induces a cascade of tumour cell death by ceasing oxygen supply to the cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com