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Hence, it can be speculated that increased chromatin accessibility mediated by NF-κB can facilitate binding of histone and DNA methylation complexes under certain conditions.
Thus it may be speculated that increased vesl-2 protein in ApoE+/−-TLR2+/+ mice fed a high fat diet and injected with P. g may lead to an increase in intracellular calcium, contributing to the increased atherosclerosis in this group of mice.
Thus, it can be speculated that increased TLRs and IL-17/Th17 IL-17/Th17alivary glands might cellsly interact and salivaryibute to the pathoglandss of SS.
It may be speculated that increased TRPV3 and TRPV4 in observed in keratinocytes may alter keratinocyte expression of NGF and other molecules, which in turn may sensitise nociceptors.
Therefore, it can be speculated that increased cAMP could also serve to support the expression of HO-1 [ 21], which is essential for the survival of FH deficient cells [ 13], as also found in our synthetic lethality screen.
In this context, it could be speculated that increased affinity of a single factor can have a negative effect on transcription, and this may explain the negative effect of bortezomib on COL1A2 synthesis.
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This result suggests that there are different cellular responses to varying HP magnitudes; for example, it can be speculated that increasing HP from 5 MPa to 10 MPa in the presence of TGF-β1 may activate additional intracellular pathways that lead to enhanced production of ECM proteins and increased biomechanical properties.
It may be speculated that increasing the number of markers leads to a further improvement of the diagnostic performance.
Therefore, it may be speculated that increasing the Nrf2 concentration may be beneficial in diseases associated with SOD dysfunction, including AMD.
It may be speculated that increasing the single dosage from 3,000 IU to 6,000 IU would have resulted in higher aFXa levels during the study period.
If sepsis related mortality has a direct relationship with high or low blood glucose concentration, it can be speculated that increasing blood glucose concentration to achieve an optimal target level could be of potential benefit.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com