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Among the components of the meningococcal T4P, the concomitantly expressed PilC1 and PilC2 proteins regulate pili exposure at the bacterial surface, and until now, PilC1 was believed to be specifically responsible for T4P-mediated meningococcal adhesion to human cells.
Among the different effects of empagliflozin (and of all SGLT2 inhibitors), none appeared to be specifically responsible for the significant reduction of cardiovascular events.
While EHD2 seems to be specifically responsible for caveolar confinement, it remains unclear which factors regulate the release of EHD2 proteins from caveolae to allow caveolar scission and internalization.
This extracellular ATP can activate both P2X and P2Y purinergic receptors, and the P2X7 receptor was originally thought to be specifically responsible for ATP-aided inflammasome activation in leukocytes, both in vitro and in vivo.
Local investigators will be specifically responsible for gaining local audit or research approval, forming a research team to identify patients and collect data and creating mechanisms to identify and include eligible patients (including daily review of operating theatre lists, team handover sheets, emergency admission lists, ward lists and operating theatre logbooks).
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They proposed that fructose was specifically responsible for adverse health effects due to its specific metabolism.
Together, this strongly suggests that neither the specific CoA-transferase function of Ach1p nor mitochondrial pyruvate supply by Mpc1p was specifically responsible for the autophagic deficiency of ach1 or mpc1 mutant cells.
He says nothing was specifically responsible for his detour, except disappointment with the roles offered him.
And we did not focus narrowly only on the people who were specifically responsible for 9/11.
The Naval Observatory is specifically responsible for standard time, time interval, and radio-frequency standards for use by the U.S. Department of Defense and its contractors.
Delegates agreed that it was useful if one part of the organisation was specifically responsible for recognising and driving forward change – and that it often helped if organisations worked together.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com