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Furthermore, it appears that APP does not have to be specifically enriched in synaptic vesicles to achieve such effects.
Interestingly, motif 1 and motif 5 have not been previously reported in any pY dataset, and could be specifically enriched in hESC.
We also identified a number of novel transcripts, which appeared to be specifically enriched in exosomes compared to total cell RNA.
Conversely, "Wnt signaling" and "Colorectal cancer" pathways were found to be specifically enriched in DEG targets of DEMs (Additional file 1: Table S4).
Moreover, this gene signature was found to be specifically enriched in PTCL/NOS vs activated CD4+ and CD8+ T-lymphocytes as demonstrated by GSEA (P-value <0.0001).
More recently, mammalian HDACs have been shown to be specifically enriched in chromatin encompassing the transcriptional start sites of transcriptionally active genes, as well as at transcriptionally silent genes that are poised for activation [ 7].
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We found that the downregulated proteins with the helicase conserved C-terminal domain were specifically enriched in the "DNA repair" category (hypergeometric test, enrichment score = 4.47, corrected P = 0.02), which has also been identified in our analysis of the functional classification.
In this regard, however, lipid acid synthesis was specifically enriched in cultivated rice, while lipid acid degradation was specifically enriched in wild rice in response to M. oryzae.
A recent report demonstrated that ETS1-binding sequences were specifically enriched in AR-targeted genes [107].
In the present study, we examined whether metallothionein-3 (Mt3), a zinc-binding protein that is specifically enriched in a brain, plays a role in obesity and hypothalamic leptin signaling in mice.
Notch4 is specifically enriched in acetylated histones along its regulatory regions in the first intron and third exon in endothelial cells [17].
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