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Risk estimation without prediction rules may be specifically difficult if several risk factors are only mildly or moderately elevated.
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In this domain, where both transmittance and reflectance of most materials are very low, the measurement of optical constants is specifically difficult, and optical data are consequently often either inexistent or uncertain.
Advance 1: Using extensive behavioral testing, we have recently discovered a set of putative recurrent computation dependent challenge images where object categorization is specifically difficult for nonrecurrent (exclusively feed-forward) deep artificial neural networks (ANNs), but are nevertheless easy for primates (both humans and macaques).
Also, HPV 18 infections have been described as being specifically difficult to detect histologically and may therefore lead to a false negative histological diagnosis [17].
The differential diagnosing of MDD, GAD and SAD is specifically difficult in adolescence, since the diagnoses are highly co-morbid [ 47].
Extremely different working habits, concerning for example usual length of consultations or participation in continuing medical education, were specifically difficult to deal with.
This will occur under conditions where the rate of folding is slow, a result of proteins that are specifically difficult to fold, or a result of the overall ER folding capacity being saturated.
However, it is difficult to see how this can be specifically related to DRM or DRR.
The coiled-coil motif has been extensively studied as a model system, and the coiled-coil domain of the yeast transcription factor GCN4 has been specifically utilized to stabilize difficult proteins for structural studies (reviewed in ref (44)).
We find that motor adaptation was specifically impaired on the most difficult to categorize trials.
When the computational model was "lesioned" by removing planning units, these more difficult problems were specifically impaired, just as in Shallice's prefrontal patients.
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