Sentence examples for be specific to cells from inspiring English sources
The mechanism for this effect is not clear, but is hypothesized to be specific to cells in quiescent states, or to result from the differential activity of the pro-apoptotic kinase JNK.
Centrosomal location of the θ isoform may be specific to cells in the G2,M phase, however, consistent with previous reports of regulated 14-3-3 14-3-3 14-3-3centrosome during celocalization[ 53].
Abrogation of the G2 checkpoint and subsequent sensitisation to DNA damage-induced cell death is suggested to be specific to cells that do not express wild type p53, as these cells depend on the G2 arrest for survival after DNA damage (Powell et al, 1995; Bunch and Eastman, 1996; Wang et al, 1996; Bracey et al, 1997).
The radiosensitization effects of PARP inhibitors (PARPi) have been shown to be specific to cells in the S-phase of the cell cycle [ 9] and are due to the collision of the persisting single strand breaks with replication forks and the formation of a lethal DNA double strand break [ 10, 11].
Fluorescence was observed both within and around the cell nucleus, was shown to be specific to cells expressing Cys326-OGG1 and only occurred in cells under conditions of cellular oxidative stress following depletion of intracellular glutathione levels by treatment with buthionine sulphoximine.
We additionally present evidence that this feature is specific to cells of hematopoietic origin.
The suppression is specific to cells and tissues overexpressing the HER-2/neu gene.
It is possible that the membrane localization of p-Stat3 (Tyr705) is specific to cells that are more malignant.
This effect is specific to cell type and NeuroD gene, as the AII amacrine cell type is refractory to the effects of NeuroD1 and NeuroD6, but uniquely sensitive to the effect of NeuroD2 on neurite targeting.
Some of the key players in this regulation are RNA-binding proteins (RBPs), which are able to create splicing programs that are specific to cell types and developmental time points.
