Sentence examples for be specific to cell from inspiring English sources
Studies of this nature are limited by the inability to differentiate responses and mechanisms that may be specific to cell type (e.g. endothelial, epithelial type I, epithelial type II, airway epithelial, macrophages, etc).
Indeed, it has been reported that their activation can be specific to cell lineage as well.
In contrast to its well established role in repressing NF- κB activation, the anti-apoptotic activity of A20 remains controversial and appears to be specific to cell type and stimulus.
BAX was upregulated in alveolar epithelial cells of both strains but was only downregulated in myofibroblasts of C57BL/6 lungs, suggesting that the regulation of apoptotic genes may be specific to cell type in the different strains of mice [ 51].
Last, the ability of BPA (but not DHT) to attenuate ERβ function appears to be specific to cell type and putatively receptor specific, as BPA had no detectable effect on ERβ expression in cells containing wild-type AR or AR-H874Y.
The mechanism for this effect is not clear, but is hypothesized to be specific to cells in quiescent states, or to result from the differential activity of the pro-apoptotic kinase JNK.
This effect is specific to cell type and NeuroD gene, as the AII amacrine cell type is refractory to the effects of NeuroD1 and NeuroD6, but uniquely sensitive to the effect of NeuroD2 on neurite targeting.
Some of the key players in this regulation are RNA-binding proteins (RBPs), which are able to create splicing programs that are specific to cell types and developmental time points.
In addition to this, further it was proposed that the inflection of surface charge on mesoporous silica nanoparticles uptake is specific to cell type [106].
This disparity did not lead to differences in cell death, indicating that jnk2 expression does not mediate cellular response to DSBs but rather is specific to cell death in response to cell cycle initiation.
