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Cre expression in this mouse line has previously been demonstrated to be specific for vascular and visceral SMCs [28].
Similar(59)
It will therefore be critical in the future to be able to build a molecular picture of VEGF-mediated permeability that is specific for vascular beds, that is dependent on the application process (i.e. how quickly VEGF levels rise), and that actually reflects changes in the barrier function of the endothelium, the VEGF type, the vascular wall history, and the response time.
Thus, AplnCreER is specific for coronary vascular ECs.
It remains unclear whether the elevated biomarkers levels are specific for scleroderma pulmonary vascular disease or if they are influenced by other scleroderma features, such as peripheral vascular disease or active tissue injury with fibrosis.
All pathways/complexes were specific for RA, including the vascular endothelial growth factor (VEGF) and the B-cell receptor signaling pathways.
Immunohistochemical staining for factor VIII-related antigen and CD34, which are synthesised by vascular ECs, are specific for the ECs of blood vessels (Bell and Flotte, 1982) and are useful for detecting tumour angiogenesis (Weidner et al, 1991).
Third, we investigated homoarginine and the risk of other adverse cardiac and vascular outcomes including MI, stroke, death due to heart failure, and the combined primary endpoint, to distinguish whether the potential effects of homoarginine are specific for SCD, or generally influence cardiac and vascular outcomes.
Vascular endothelial growth factor (VEGF) is a mediator with potent angiogenic, mitogenic, and vascular permeability-enhancing activities that are specific for endothelial cells.
These effects were specific for FAK, as replacement with a non-targeted sequence for FAK allowed the formation of stable vascular structures.
The timing is specific for a reason.
Importantly, this relationship was specific for females.
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