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A set of previously described primers that have been shown to be specific for human group B rotavirus gene segment 8 were also found to amplify the cognate gene from the CAL isolates.
The three NB-specific monoclonal antibodies used were supposedly raised against bovine NB, but were also claimed to be specific for human antigens (Nanobac Oy).
More recently, though, Vatakis, Ghazanfar, and Spence (2008) qualified these findings and reported that the effect may be specific for human speech.
Denosumab suppresses osteoclast formation in humans by binding to RANKL, which in turn inhibits RANK activation; immunoassays showed denosumab to be specific for human RANKL.
Previous studies (8,47) suggested that abundant interspersed segmental duplications may be specific for human and great apes genomes and play a vital role during the evolution of their gene families.
Hence, as shown in a recent study [ 24], the markers produced from studies on rodents may not be specific for human discs and may not be relevant for repair studies on human discs.
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The rs1044396 SNP is apparently not found in the Chimpanzee genome and is assumed be specific for humans.
Previously, it was shown that APOA1, APOA2 and APOA5 are upregulated by PPARα agonists, which was found to be specific for humans [38] [41].
This aspect may be specific for humans only.
Eculizumab is a humanized monoclonal antibody that is specific for human C5 complement protein and prevents the activation of terminal complement complex C5b-9.
The human factor IX antigen, one-stage human factor IX activity, human factor IX-directed IgG, and human factor IX Bethesda inhibitor assays were performed as previously described and are specific for human factor IX (although not specifically standardized for factor IX variants, e.g., FIXR338L).
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