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The first transitions may be small changes in the protein tertiary and quaternary structure.
For example, there could be small changes in the expression of a number of chaperones that affects the cellular environment and enables amyloid resolubilization.
The advantage of our analysis being performed at the level of broad biosynthetic series is that in this way we were able to detect evolutionary conservation of fertility-linked compounds even if there would be small changes in the bioactivity of particular compounds across the study species.
The second is that, no matter how exciting they may be, small changes in minor bits of wetware do not explain the one really spectacular feature of brain evolution – the sheer size of the brains with which some species saddle themselves.
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We were concerned, however, that measurement of CO might be compromised by a shorter rebreathing period because there would be smaller changes in the measured variables, fewer sampled breaths and incomplete equilibrium [ 5].
There are small changes in the action, too.
At w = 10 mm, the waveform is slightly changed, and there are small changes in the phase and amplitude (Fig. 7 a1)).
The possible reason may relate with the integration parameters, the peak area changed at the same integration parameters when there were small changes in experimental parameters.
This is mainly due to the fact that there are small changes in the voltage scaling from 1.1 to 0.9 V.
Analysis of pairs of compounds with high structure similarity revealed the presence of single-, duand, and 'pan-receptor' activity cliffs, that is, small changes in structure with high changes in potency for one, two, or three receptor subtypes, respectively.
Equivalent electron states (similar wavefunction but localized at differents dots) do not have the same energy since dots have different sizes as well as there are small changes in the strain distribution (Table 1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com