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Epirubicin tended to be slightly less efficacious than doxorubicin (ORR, 18% vs 25%; P =.33), but produced less hematological toxicity and less nausea and vomiting.
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The semi-quantitative findings indicated that Cpd α is slightly less efficacious than TCBZ itself in causing histological damage to the reproductive structures of TCBZ-sensitive flukes, and that, like TCBZ, it caused no histological damage in flukes of the TCBZ-resistant isolate.
Notably, fluorenyl compounds 15 and 16 displayed inhibition of TTR fibril formation comparable to the well-known TTR amyloid inhibitor diflunisal (69% for 15 and 16 Vs 63% inhibition for diflunisal [25]), while ortho-substituted aryl derivatives 11 and 13 were slightly less efficacious.
Results of trials comparing the efficacies of topical with oral NSAIDs have generally found that topical NSAIDs are slightly less efficacious than oral agents [ 61, 62].
Etorphine is highly efficacious at the MOP receptor with a maximum stimulation of 115%, and is slightly less efficacious at the DOP and KOP receptors, with maximal stimulations of 60 and 98% respectively (Xu et al., 2008).
Similarly, in pristane-accelerated lupus, dual B cell therapy was superior to CYC treatment in all measures except for overall survival, where dual B cell therapy was slightly less efficacious.
The AZD6244 resistance signature shows relatively good agreement with our inhibitor screen results (Table 3 ), such that EGF stimulated PMC42-LA cells are susceptible to AZD6244, the inhibitor is slightly less efficacious within EGF stimulated MDA-MB-468 cells, and MDA-MB-468 cells grown under hypoxic conditions are not affected by AZD6244.
PKF118-310 and CGP049090 were slightly less effective.
Churches would be slightly less than that.
He was slightly less abrasive.
They are slightly less efficient than derailleurs.
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