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These findings expand the potential of the cystine-knot scaffold for future studies where multiple knottin loops can be simultaneously engineered to bind to exogenous targets.
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Firstly, we here report a DHP that is simultaneously engineered to incorporate a miRNA recognition sequence, an output segment and output's complementary fragment.
Finally, EGFR-NCE mechanistically depends on EGFR ubiquitination, as the two events can be simultaneously re-engineered on a phosphorylation/ubiquitination-incompetent EGFR backbone.
Its famous soup dumplings, xiao long bao, may not be as precisely machined as the ones at Din Tai Fung, but the thicker wrappers are soulful, engineered to absorb just enough black vinegar, simultaneously chewy and tender.
First, NSCs can be engineered to produce different genes.
As A. baylyi ADP1 has been engineered to produce several valuable biochemicals, it could be used to produce these molecules as a side stream in lignocellulosic biofuel production, while simultaneously making the biofuel production economically more feasible.
The Klebsiella oxytoca was engineered to produce 2,3-butanediol (2,3-BDO) simultaneously utilizing glucose and galactose obtained from a Golenkinia sp. hydrolysate.
Orthogonal tRNA/synthetase pairs have been engineered to incorporate Uaas into proteins in response to UAG, yet the presence of RF1 makes the meaning of UAG ambiguous, being a stop signal and a Uaa simultaneously.
Its xylose metabolism was engineered to enable its use in lignocellulosic fuel production, such that the engineered strain could utilize xylose and glucose simultaneously for lipid production [ 17].
It is engineered "to lock in hydration".
"The process is engineered to avoid that," he says.
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