These findings suggest that both sets of detected oligomiRs are actually co-expressed in oligometastatic lesions from two independent clinical cohorts, but cannot be simultaneously detected due to the limited statistical power of these smaller sample sets.
Five such independent quantities, three strains and two velocities, have to be simultaneously detected and processed in an appropriate way in order to get intensity readings.
The protocol is rapid and specific to 5mC, allowing all three base modifications to be simultaneously detected in a single sequencing experiment.
To explore whether MCPC can also be used is some cases where more than one target need to be simultaneously detected, a model study was performed by genotyping five common Chinese β-thalassemia mutations in β-globin gene [11].
Although we showed that MCPC can be used in situations where more than one targets need to be simultaneously detected when signal intensity ratios are considered (Figure 4 and Table 2), one of the main drawbacks of MCPC strategy still lies in its less or even unsuitability for simultaneous detection of multiple targets in one reaction.
Different types of primitives can be simultaneously detected using iterative model fitting [7, 8].
Furthermore, some nuclear transcription factors can be simultaneously detected, e.g., Foxp3 in CD4+CD25highEdU+ cells (Fig. 3).
When using NAD(P H-FLIM, all NADH- and NADP H-FLIMdent enzymes which pallicipate in biochemicandreactions within the cell are simultaneously detected (up to senzymeshundred enzymes).
In cellular model, ΔΨm loss and cytochrome c release were simultaneously detected in response to ABT-737 [39], [39] contrary to what was observed with our conditions in cell-free system.
Light enters the tissue at a source position (s1), while light emerging at several, relatively short, distances (typically 0 to 3 mm away) from the source position (d1 to d7) is simultaneously detected.
