Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
be significantly implicated
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "be significantly implicated" is correct and usable in written English.
It can be used when discussing the involvement or connection of someone or something in a particular situation, especially in a serious context. Example: "The investigation revealed that several individuals may be significantly implicated in the financial fraud scheme."
✓ Grammatically correct
Science
Academia
News & Media
Alternative expressions(4)
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
2 human-written examples
Both TLR4 SNPs under investigation were found to be significantly implicated with HCV-infection among Saudi Arabian population.
A general assertion is that for ACh to be significantly implicated in cognitive tasks, these tasks must be difficult and require effortful attention [ 11, 59].
Human-verified similar examples from authoritative sources
Similar Expressions
58 human-written examples
But whether Linn's partial pre-emption of state libel remedies is applicable obviously cannot depend on some abstract notion of what constitutes a 'labor dispute'; rather, application of Linn must turn on whether the defamatory publication is made in a context where the policies of the federal labor laws leading to protection for freedom of speech are significantly implicated.
Academia
A case/control study investigating genetic variants of TNFRSF1A and 1B in association with the three main NOD2 variants, reported that one out of two SNPs from each gene was significantly implicated in the CD cohort [44].
Science
This mutation is significantly implicated in both sporadic and inherited human colorectal carcinogenesis [ 12- 14].
Science
The proposed technique predicted genes that are significantly implicated in cellular processes required for tissue regeneration after injury.
Science
Retinal iron levels increase with age [ 1322], iron is significantly implicated in AMD [ 1323- 1329], and iron chelation may help to reverse the process [ 1330].
Science
Finally, we note that NGAL is significantly implicated in pregnancy, and was even named uterocalin in mice to reflect its high expression in the uterus [ 361, 537- 539].
Science
It has been significantly implicated in the initiation and progression of glioblastoma (GBM), a very aggressive class of brain cancer [ 1- 3], where the median survival time of GBM patients is approximately 15 months [ 4].
This is reminiscent of the relevant SNPs of the DTNBP1 gene, which are mostly intronic and have been significantly implicated in the executive function of healthy controls [ 30], in cases belonging to early-onset families with functional psychosis disorders [ 65], and in the spatial working memory in patients with schizophrenia [ 66].
Science
Nevertheless, the loss-of-function rare variants in the TREX1 and CYP27B1 genes have been significantly implicated in SLE and MS patients respectively (13, 14), suggesting the possibility that rare genetic variants may have a role in risk susceptibility for some of the less prevalent autoimmune diseases.
Expert writing Tips
Best practice
Use "be significantly implicated" to denote a noteworthy connection or involvement, especially when suggesting the potential for consequences or further investigation. Ensure the context aligns with the formal tone of the phrase.
Common error
Avoid using "be significantly implicated" in casual or informal writing. Opt for simpler and more direct alternatives like "be involved" or "be connected" to maintain an appropriate tone.
Source & Trust
84%
Authority and reliability
4.3/5
Expert rating
Real-world application tested
Linguistic Context
Be significantly implicated functions as a passive construction, indicating that someone or something is involved in a particular situation or event to a notable degree. Ludwig AI confirms its correct usage in formal contexts.
Frequent in
Science
60%
Academia
20%
News & Media
20%
Less common in
Ludwig's WRAP-UP
In summary, the phrase "be significantly implicated" correctly denotes a notable connection or involvement, especially in formal contexts. As Ludwig AI states, it’s grammatically sound. While not highly frequent, it’s commonly used in scientific, academic, and news media sources. When a less formal tone is needed, you can replace the phrase with alternatives like "be deeply involved" or "be heavily connected". Using this phrase suggests a serious connection that may have future repercussions.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
be deeply involved
Emphasizes a strong degree of participation or connection, replacing 'implicated' with 'involved'.
be heavily connected
Highlights a strong association or link, differing from 'implicated' by focusing on the nature of the connection.
be strongly associated with
Focuses on the correlation or relationship between elements, rather than direct involvement.
play a major role
Indicates a substantial contribution or influence, shifting the focus from implication to active participation.
be centrally involved in
Highlights the importance of involvement, emphasizing a key role in the context.
be critically linked to
Stresses the essential nature of the connection, moving away from the potentially negative connotation of 'implicated'.
have a substantial impact on
Shifts the focus to the effect or consequence, rather than direct participation.
be closely tied to
Emphasizes a close relationship or association, differing from 'implicated' by focusing on the nature of the connection.
be significantly entangled with
Suggests a complex and intertwined relationship, adding a layer of complexity not present in the original phrase.
be substantially concerned with
Implies a strong focus or interest, rather than direct involvement.
FAQs
How can I use "be significantly implicated" in a sentence?
You can use "be significantly implicated" to indicate a notable connection or involvement, particularly when discussing potential consequences or further investigations. For example, "The evidence suggests that the company may be significantly implicated in the scandal."
What are some alternatives to "be significantly implicated"?
Alternatives include "be deeply involved", "be heavily connected", or "be strongly associated with", depending on the specific nuance you wish to convey.
Is it correct to use "be significantly implicated" in formal writing?
Yes, "be significantly implicated" is generally appropriate for formal writing. It conveys a serious and consequential connection and is often found in academic, scientific, and legal contexts.
What's the difference between "be implicated" and "be significantly implicated"?
While both phrases suggest involvement, "be significantly implicated" emphasizes a stronger and more noteworthy connection. The addition of "significantly" intensifies the degree to which someone or something is involved.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
84%
Authority and reliability
4.3/5
Expert rating
Real-world application tested