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Osteoblastic- and osteoclastic-associated genes were found to be significantly expressed within the increased expression groups.
Another key pathway identified to be significantly expressed in the increased expression group (Table 1) was the cellular process pathway of Wnt signaling, which was found to be significantly expressed at the study timepoints of 1, 3, 5, and 7 days post-ablation.
One of the major pathways identified in our model to be significantly expressed in the increased expression group (Table 1), was the molecular function network of matrix metalloproteinases (MMPs), which was specifically determined to be significantly expressed at 1, 3, 5, 7, and 10 days post-ablation (Table 2 and Table 3).
Signaling pathways known to be in involved in the self-renewal and osteogenic differentiation of MSCs are Wnt signaling, BMP/TGF-β signaling, and notch signaling[47], which are pathways identified in this study to be significantly expressed within the increased or variable expression groups, respectively.
Thus any protein remaining with a positive expression value is considered to be significantly expressed [ 76].
In this study, eight somite/muslce-expressed SET domain genes were identified to be significantly expressed in somites and muscles at certain stages (Figure 5A and B, right).
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The expression of Bo-FT was significantly expressed in the HT1 rather than HS genotype (Fig. 8b).
SOD1 protein however, was significantly expressed in N0 cells in accordance with the expression of SOD1 genes with PB treatment.
Based on OsSUT2 promoter::GUS expression in germinating seeds of transgenic rice, OsSUT2 was significantly expressed in the embryos and aleurone layers.
Using human brain tissues, we identified 401 proteins that were significantly expressed in recurrent AO.
Early osteogenic differentiation markers of hAMSCs were significantly expressed on the collagen-keratin-nHA scaffolds.
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