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Genes involved in mitochondrial function and electron transport were generally downregulated, however these functions were not found to be significantly changed compared to controls.
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However, neither memory scores (Fig. 3r) nor BRP staining levels (over the central brain) (Fig. 3t v) were significantly changed compared to controls.
Global gene expression analysis reveals that the gene profiling in iN cells is significantly changed, compared with that in the parental fibroblasts, supporting the notion that Ink4/Arf and hTERT may act as a 'master switch' to coordinate a set of defined factors in regulating cell reprogramming.
The integrity of the SiC shell (no crack within the shell) can be assessed by the ultrasonic vibration spectrum of the HTR particle, which is significantly changed, compared to the reference spectrum of a defect-free particle.
In total they detected 1006 macrophage proteins, and 244 proteins were significantly changed compared with non-infected controls.
In this model, LV volumes were significantly changed compared to a control population, leading to a LV dysfunction.
In this model of diabetic rats, normalized LV volumes were significantly changed compared to a control population, leading to a LV dysfunction.
Neither the expression of claudin-1 and -2 nor of ZO-1 and ZO-2 was significantly changed compared to mock-transfected clones.
The narrow pore is filled with four H2O molecules and is bound by carnosine 1, in which the torsion angles of the peptidic chain were significantly changed compared to those of all the other structures.
The characteristic blocking of the Ca2+ release channel in a closed state by 100 μM ryanodine was apparently preserved in this RyR2 mutant, but the Ca2+-dependent ryanodine binding was significantly changed compared with the other RyR2 types studied.
* IC50 was significantly change compared with pNL4-3 WT, P < 0.05.
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CEO of Professional Science Editing for Scientists @ prosciediting.com