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The details of CTCF binding and its consequences are less well studied at other imprinted loci; however, its insulator function and role in establishing higher-order chromatin function appear to be shared features of other mammalian imprinted loci which bind CTCF [ 5, 15- 17].
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Nonetheless, there are shared features of the motifs between maize and rice, particularly the 5'TCTCT' and the 3'CTAGTGT'CTAGT
Impaired translation and a positive response to l-leucine are shared features of zebrafish models of the cohesinopathies, including RBS and CdLS models.
Weak activation of Stat3 and lack of biological response to Lif are shared features of human embryo-derived stem cells and mouse EpiSCs (Brons et al., 2007; Daheron et al., 2004; Tesar et al., 2007; Thomson et al., 1998).
Secondly, TGF-β-induced epithelial-mesenchymal transition generates self-renewing cells, a process also implicated in a higher risk of tumor metastasis, as invasiveness and self-renewal are frequently shared features of stem cells, TICs and metastatic cells [ 15, 16].
To determine whether CGI chromatin is developmentally programmed at specific genes or is imposed by shared features of CGI DNA, we integrated artificial CGI-like DNA sequences into the ESC genome.
No specific ancestral species is identified, but we recognise that there is a distinct lineage of animals that can be grouped together by shared features of their anatomy that we call dinosaurs.
Recently, it has been proposed that a generalized up-regulation of xenobiotic detoxification pathways may be a shared feature of long-lived mutants and a key mechanism of longevity assurance (McElwee et al., 2004; Shore et al., 2012; Steinbaugh et al., 2012).
Cognitive bizarreness seems to be a shared feature of dreaming and psychotic mentation, beyond diagnostic categorizations.
Elevation of ATF4, at least in liver, thus seems to be a shared feature of diets, drugs, genes, and developmental alterations that extend maximum lifespan in mice.
Moreover, the ability to bring distant DNA segments into proximity appears to be a shared feature of proteins with C-terminal PAKKA-type repeats.
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