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Exact(6)
Some patients might be sequenced multiple times as a tumor spreads and mutates.
Therefore some haplotypes may be sequenced multiple times, while others may not be sampled at all.
If the lifetime of the polymerase is long enough, both strands can be sequenced multiple times (called "passes") in a single CLR.
Because overlapping segments of the same gene may be sequenced multiple times, it is customary to assemble overlapping ESTs into a single consensus unigene.
If a target DNA is too long to be sequenced multiple times in a CLR, a CCS read cannot be generated, and only a single subread is output instead.
For example, the large genomes provided a control sample that could be sequenced multiple times at the same titration level throughout the course, facilitating the students' introduction to the sequencer, and providing the instructor a tool to evaluate each student's progress.
Similar(54)
Each base of the genome was sequenced multiple times (∼300-fold coverage), which permitted easy identification of partially methylated sites.
The transmission event data set of CUSH was composed by sequence samples of patients taken at different times and disease stage: some patients were sequenced multiple times either before treatment initiation or at treatment failures, whilst others had only one sequence sample taken.
This is likely to be caused by a small sample size (N = 645 CDSs) which also features several genes which are overrepresented due to being sequenced multiple times from different strains (one gene alone represents over 10% of the total dataset).
Each fragment of DNA is sequenced multiple times.
All samples were sequenced multiple times bidirectionally to verify the induced mutation identified from TILLING.
Related(20)
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