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Furthermore, positive cultures may have to be sent to reference laboratories, due to limited availability or experience with fungal resistance testing on site, thus causing delay of effective therapy.
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Throat swab samples from suspected cases were sent to reference laboratories for confirmation.
Pneumococcal isolates collected through ABCs were sent to reference laboratories for susceptibility testing by broth microdilution according to the methods of the National Committee for Clinical Laboratory Standards (NCCLS) (13 ).
If this analysis could not be done at a local level, stool samples, RNA, or sequence information was sent to reference laboratories.
A cotton swab transport medium will be used, that will be sent to the reference laboratory within 24 hours, as standard practice.
Samples collected into PAXgene blood RNA tubes should be sent to the reference centre within 48 h at room temperature, or can be stored locally at −80°C for up to 12 months before analysis.
Identifying some strains with provisional serovars of Shigella spp. for the first time from Kolkata, India, indicates that all provisionally identified Shigella strains should be sent to a reference laboratory for typing and further characterization.
Since 1999, residual samples from cases reported by local laboratories are requested to be sent to the national reference laboratory for confirmation by an alternative IgM assay (with or without avidity testing) (23 ).
However, the organism-specific application of these strain-typing methods, often requiring isolates to be sent to a specific reference laboratory, in practice means that many infection clusters remain untyped.
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There is likely an under reporting of NTM because it is not notifiable, and in most countries samples/isolates need to be send to the reference laboratory for detection and/or identification of NTM.
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