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This will be sensitive to sequence coverage and to filter thresholds such as read depth and quality scores.
In this species, the function of URE2 in the forebrain seems to be completely conserved despite variation in the sequences, which highly contrasts with our results from transgenic assays in zebrafish where expression in the diencephalon seems to be sensitive to sequence variations.
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We show that current non-parametric covariation statistics are sensitive to sequence misalignments and that this sensitivity can be used to identify systematic alignment errors.
These data allow us to infer the relationships between experimentally important strains of yeast and provide insight for experimental designs that are sensitive to sequence variation.
However, given the high degree of overlap between the SNAP score distributions of variable and non-variable exons, it is not possible to predict a priori whether an individual SNAP gene model is sensitive to sequence polymorphisms.
Furthermore, circularization by RNA ligase is sensitive to sequence bias [ 13].
The repair efficiency of base base mismatches is sensitive to sequence context and increases with increasing G and C content in the neighboring sequence.
48 However, most of the predictive programs assume a uniform and ideal strength to the predicted regions, albeit being sensitive to sequence breaks like stutters and stammers.
Thus, the number of OTUs is sensitive to sequencing error of 454.
As the algorithm is sensitive to sequencing errors, low-quality reads were filtered, and high-quality reads were used for de novo assembly.
The subject of our work is the quality assessment of a set of exome genotypes, thus our metric needs to induce a topology that is sensitive to sequencing errors while being robust to true genetic differences.
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CEO of Professional Science Editing for Scientists @ prosciediting.com