Sentence examples for be sensitive to regulation from inspiring English sources

Our data add a direct pathogenic link of miR-20b to autoimmune inflammation and suggest miR-20b-related processes as a possible therapeutic target in MS. Regarding such processes, our in silico promoter analysis indicates that the here identified candidate including miR-20b may be sensitive to regulation by the NF-kB pathway known as a central downstream target of α4 β1 signaling.

CYP2S1 expression is sensitive to regulation by endogenous and exogenous chemicals.

Less is known about the direct effects of testosterone on articular chondrocytes, but cells from both male and female donors express receptors for testosterone and DHT [ 72], indicating that these cells are sensitive to regulation by androgens.

In our hypothesis, yeast species that have been selected for the most effective mechanisms providing protection against bile acids (and other environmental xenobiotics) are expected to evolve the most effective anti-aging mechanisms that are sensitive to regulation by bile acids (and, perhaps, by other environmental xenobiotics).

One could envision that during evolution yeast have lost the ability to synthesize bile acids but have maintained the life-extending response to these biologically active molecules by retaining certain longevity-related processes that are sensitive to regulation by bile acids.

A stimulatory effect of female sex hormones has been reported in experimental studies, 31 and production of B-type natriuretic peptide may be sensitive to oestrogen regulation.

Furthermore, depletion of GNL2 or SEC13 in HeLa cells led to a marked upregulation of three endogenous transcripts that were previously reported to be sensitive to NMD regulation [ 7, 28] (Fig 4E).

These genes may be regulated in a more acute fashion by external stimulation, such as insulin or cholesterol, or may not be sensitive to diurnal regulation in the adipose tissue of mildly obese subjects.

Moreover, after removing these testes-biased genes, these mito-sensitive genes were also randomly-represented on a list of genes known to be sensitive to Y chromosomal regulation (mito-sensitive among Y-sensitive: 6.2%, general representation of Y-sensitive among all genes on the Affymetrix chip: 5.2%, odds ratio: 1.15, P = 0.39).

These mito-sensitive genes are also over-represented on a list of genes known to be sensitive to Y chromosomal regulation (mito-sensitive among Y-sensitive: 7.5%, general representation of Y-sensitive among all genes on the Affymetrix chip: 5.8%, odds ratio: 1.38, P = 0.008).

Consistent with these predictions of SC, we indeed found that these mito-sensitive genes are both under-represented on the X-chromosome, and over-represented on a list of genes whose expression has been shown to be sensitive to Y chromosomal regulation.