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Therefore the tumour may be sensitive to hormone manipulation therapy.
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Yet even when these factors are taken into account, they do not completely explain why black women have poorer outcomes, particularly those with the type of breast cancer that is expected to be sensitive to hormones.
Hormone treatment: Some breast cancers may be sensitive to hormones - eg oestrogen.
CYP enzymes mediate the metabolic activation of numerous precarcinogens, and they can promote or suppress tumor development via hormonal control in cancers that are sensitive to hormone concentration (e.g. breast cancer).
can mediate significant cytotoxicity to AN3CA cells (estrogen receptor negative endometrial carcinoma cells) which are sensitive to hormone therapy.
This kind of kidney disease can self-subside and is sensitive to hormone drugs with high cure rate of almost 90%.
Moreover, not all ER positive breast cancer patients respond to endocrine therapy; some of the patients who were sensitive to hormone therapy developed resistance; however, the mechanism is unclear [ 25, 26].
Published studies evaluating the role of cyclin D1 in breast cancer support the current observations of the activity of a CDK4/6 inhibitor in luminal ER-positive breast cancer, its synergism with tamoxifen in cell lines that are sensitive to hormone manipulation, as well as the reversal of resistance of those that have acquired a resistant phenotype in the face of anti-estrogen therapy.
Some breast cancers are sensitive to hormones such as estrogen (E2) [ 2].
Breast cancer occurs more frequently in postmenopausal women than in younger women, and a higher proportion of these older patients have tumors that are sensitive to hormones.
Older seedling leaves may be sensitive to this hormone, causing leaf necrosis.
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