Sentence examples for be sensitive to cell from inspiring English sources

We hypothesized that, given their likeness to DNA repair compromised hereditary BRCA mutated breast cancers, triple-negative breast cancer may be sensitive to cell killing by Chk1 inhibitors.

Our results suggested that the CLL cells could be sensitive to cell death induced by smac-mimetic and particularly sensitive to combined CD40L and smac-mimetic treatment, in view of the enhanced NF- κB signaling and TNF α production.

Water has previously been reported to be sensitive to cell death, and its reduction may reflect a progressive loss of tumor cellularity and edema for at least 1 week [ 23, 32] or for 4 weeks [ 27] after initiation of NAC.

Because hmo1Δ strains are slow growing, showing slower progression throughout the cell-cycle (Lu et al, 1996), and PCNA modifications with SUMO and ubiquitin are expected to be sensitive to cell-cycle changes and replication delays (Hoege et al, 2002), we established a conditional degron system (hmo1-AID), in which Hmo1 depletion is induced by addition of auxin (Nishimura et al, 2009).

In mouse brain slices, α was strongly location-dependent, ranging from 0.16 in thalamus to 0.22 in brainstem, and was sensitive to cell volume changes.

We have observed previously that both its intracellular localization and expression levels are sensitive to cell density, suggesting that it may crosstalk with Hippo signaling.

For instance, upon expression of shPHB2-0, cells already showed a decrease in cell-cell contact and cell-matrix formation and were sensitive to cell density (Fig 4A).

Since primary fibroblasts are sensitive to cell density, we assessed the effect of NPD versus DI based media on cell proliferation with different initial seeding density.

The Δ mpkA mutant strain is sensitive to cell-wall active compounds, oxidative stress and heat shock.

Yet, in our case, the model's performance may be sensitive to the cell tower selected for tuning the parameters.

Thus, the effects of STAMP appear to be sensitive to unknown cell-specific factors.