Sentence examples for be seen whether cox-2 from inspiring English sources

It remains to be seen whether cox-2 inhibitors will actually help prevent cancer.

It remains to be seen whether COX-2 inhibitors and Ep-CAM directed monoclonal antibodies turn out to be efficacious for the treatment of other epithelial cancers such as breast carcinoma.

The same trend was seen for the COX-2 G-765C polymorphism (p = 0.06).

This fact can be seen as COX-1 (triangles) and COX-2 (squares) define two distant clusters.

In normal tissue a linear relationship could be seen between Cox-1 and Cox-2 expression.

Strong COX-2 expression was seen in MOR/P and A549 cell lines and weak COX-2 was present in H460 cell lines.

These complexities were well demonstrated in a recent study where an increase in VEGF levels in Cox-2 positive and Cox-2 negative pancreatic cancer cells was seen after treatment with high concentrations of Cox-2 inhibitors, suggesting that the relationship between Cox-2 protein inhibition and VEGF or Cox-2 promoter expression may not always be tightly linked [47].

Slightly lesser effects were observed with indomethacin, and no effects were seen with a selective COX-1 inhibitor, suggesting a COX-2-dependent pathway is involved [ 66].

COX-2 over-expression was seen in 19 (48.7%) cases.

COX-2 inhibitors other than celecoxib can downregulate Bcl-2 [ 19, 22]; whether other COX-2 inhibitors would downregulate Bcl-2 expression to a greater extent than celecoxib remains to be seen.

However, it is still unclear whether COX-2 expression is controlled through PPAR γ signalling in ovarian carcinoma cells.