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Fat body-derived DILP6 itself may be secreted and function as this hormone.
The ability of intestinal EGL-3 to rescue egl-3 daf-28 lf) daf-28 lfthat EGL-3 can be suggests and functhat extracellularly to procans ILPs.
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In skin washing fluids of healthy adult human skin RNase 7 is readily detectable, suggesting that it is secreted and functions primarily outside the keratinocyte [ 21].
Alternatively, the processed 15 kDa ISG15 molecule can be secreted and exerts immunoregulatory functions on peripheral blood lymphocytes [5].
It has also been reported that S100A4 can be secreted, and suggested extracellular functions include induction of angiogenesis [ 9], stimulation of cell motility [ 10], and stimulation of neurite outgrowth [ 11].
Accordingly, Drosophila Spacemaker and other proteins which share several of EYS domains have been found to be secreted and to have a structural function, such as SCUBE [ Yang et al., 2002] or CMG-2 [ Bell et al., 2001].
In the current study, calmodulin-like skin protein (CLSP), a calmodulin relative with an undefined function, was shown to be secreted and inhibit neuronal death via the htHNR with an EC50 of 10 100 pℳ.
It is well established that Leishmania releases virulence factors that promote parasite survival in macrophages, so we tested whether L. mexicana MCA is secreted and thereby modulates functions of the host cell to promote Leishmania replication.
It has been shown that tRNA synthetases, including GlyRS, are secreted and have non-canonical functions (12, 31).
It is localized in the calicoblast ectoderm, from which it is secreted, and has a CA catalytic function.
Next, we employed a more stringent approach to analysing the seminal vesicle proteome, performing a single analysis of proteome composition and focusing solely on that proportion of the proteome that is secreted and that could thus have functions relevant to sperm competition outcomes within the female reproductive tract.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com