As well as identifying loci controlling qualitative Mendelian traits, mapping populations can also be used to find quantitative trait loci (QTL), i.e. regions of the genome contributing to complex multigenic traits which are scored as continuous data.
It is important to emphasise that the risk attitudes were scored as continuous factors, and, for instance, an OR of 1.03 means that, for every 1-unit increase in the score, a 3% increase in the odds of taking a PSA test is expected.
The PHQ measures presence of DSM-IV major depression symptoms and can be scored as a continuous or categorical screening measure for depression.
The inventory was scored as a continuous measure (score range 9-54), with a higher score indicating greater body dissatisfaction [ 47].
For analysis we conducted LMM by taking the number of females from which progeny was scored as a continuous covariate, generation as a fixed independent variable and block as the random independent variable.
c-MYC mRNA expression was scored as a continuous variable (log10 transformed to obtain an approximately normally distributed variable, 0.01 added if c-MYC mRNA level was not detectable).
In the univariate and multivariate Cox regression model, total Cat X was scored as a continuous variable on the log scale using base 2, which means that hazard ratios (HR) are for two fold differences.
MSSI scores, which were collected as continuous numeric values, were categorized into tertiles for the analysis.
Because standardized cutoffs for the BIS15 do not exist, scores were kept as continuous outcomes.
Because standardized cutoffs for the BPAQ-SF do not exist, scores were kept as continuous outcomes.
