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A critical issue concerns the question of whether NOD1 or NOD2 activity can be safely suppressed without causing undue detriment to host defences against endogenous microflora and pathogenic micro-organisms.
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Long-term study can only prove if it may be safely used without disturbing the ecosystem.
Human exploratory missions cannot be safely performed without a substantial reduction of the uncertainties associated with different space radiation health risks, and the development of effective countermeasures.
It is questionable as to how advanced laparoscopic procedures can be safely introduced without compromising the patient.
In our patient, although abnormal blood flow remained after embolization, surgical resection could be safely performed without any complications.
However, there is growing evidence that occult pneumothorax can be safely treated without thoracostomy in non-ventilated patients [19].
GM-CSF supplementation can be safely used without deteriorating pulmonary gas exchange function.
The semi-dry sample can then be safely stored without risk of nuclease activity.
Moreover, laparoscopic segmental splenic flexure resection can be safely completed without identification and isolation of the middle colic vessels [ 11].
These can be safely deleted without affecting your system.
Sand, already installed in play areas, cannot be safely cleaned without leaving residues that could harm children.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com