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Adding anti-IFN-γ led to an overall reduction in migration, however, the reduced migration of TCRtgCD152−/− Th1 cells could not be reversed by blocking IFN-γ (Fig. 3).
Our data show that mitochondrial dysfunction can be reversed by blocking ROS production.
The PD-L1+ monocytes effectively suppress tumor-specific T cell immunity and contribute to the growth of human tumors in vivo, which can be reversed by blocking PD-L1 on these monocytes.
An example of the former mechanism is development of tamoxifen resistance in MCF-7 cells by transfection with the gene for the ErbB2 receptor, which can be reversed by blocking activity of the receptor [ 25].
However, unlike the situation in mouse, the reduced stability of dmAgo1 in these cells could be reversed by blocking the action of the proteasome, suggesting that the turnover of unloaded dmAgo1 involves the proteasome (Smibert et al, 2013).
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The present study was designed to determine which ulcerogenic effects of the NSAID diclofenac sodium are reversed by blocking the endocannabinoid catabolic enzyme monoacylglycerol lipase (MAGL).
This depression was reversed by blocking GABA inhibition with picrotoxin (100 microM .Propofol does enhance inhibition in brain slices at a concentration of 0.63 microM in the superfusate, which produces brain concentrations corresponding with those achieved in vivo, but equilibration requires several hours.
Using lymphomas cells grown ex vivo we reproduced the synergy observed in mice between chemotherapy and elongation inhibition and show that this is reversed by blocking protein degradation with a proteasome inhibitor.
This was associated with constitutive IL-10 production and was reversed by blocking IL-10 function.
The EMT phenotype of breast cancer cells induced by CAF-CM was reversed by blocking TGF- β1 signalling.
The effect of IL-10 on TNF-α production by memory B cells was reversed by blocking with IL-10/IL-10 IL-10/IL-10 IL-10/IL-10
More suggestions(16)
be reversed by blockade
be won by blocking
be reversed by feeding
be reversed by increasing
be observed by blocking
be determined by blocking
be attenuated by blocking
be targeted by blocking
be normalised by blocking
be reversed by modifying
be obtained by blocking
be boosted by blocking
be starved by blocking
be caused by blocking
be rescued by blocking
be enhanced by blocking
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