Sentence examples for be responsible for replication from inspiring English sources

Although the assay used did not allow clearly defining the mechanism, the study suggests that low efficiency of origins located within CFS, with respect to those in nonfragile regions, may be responsible for replication perturbation along fragile sites.

DNA-binding activity is associated with its C-terminal DNA-binding domain (DBD), while the N-terminal transactivation domain (TAD) is responsible for replication and transactivation functions.

The West Nile virus (WNV) genome contains a single RNA-dependent RNA polymerase (RdRp) gene, which is responsible for replication of the viral genome and, as such, is an important target for antiviral therapy.

Polymerase gamma (Pol γ) has a similar error rate (10−5 10−6) and is responsible for replication of the mitochondrial genome (McCulloch and Kunkel 2008).

ORF2 encodes a protein of approximately 95 kDa with critical endonuclease and reverse transcriptase activities as found in mammalian L1s, and is responsible for replication of the element.

In addition, orc/cdc6 genes were found on most of the extrachromosomal elements (Table  1), suggesting that the orc/cdc6-associated replication origins are responsible for replication initiation on most of these replicons.

It is thus possible that the downstream origin (which positions (CAG n in the lagging strand template) is responsible for replication and expansion of the TNR in the transgenic DM328 cells.

Since the secondary structure – which is responsible for replication speed – of such parasites is not constrained by any functional criteria like metabolic efficiency we assume that the replication rate k p of parasites is the highest of all replicator types in the system.

Unlike other members of the polA family such as the E. coli DNA pol I, which are low processivity enzymes involved in DNA repair, T7 gp5 is responsible for replication of the phage chromosome with an associated high processivity of thousands of bp per event [ 58].

* Rep genes encoded in these replicons might be responsible for DNA replication initiation.

DNA lesions resulting from oxidative DNA damage caused by endogenous ROS could be responsible for the replication stress.