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Their inclusion in this pilot study was necessary to establish the tolerability and safety of this potentially antifibrotic therapy in later-stage patients, which would be requisite for their inclusion in future controlled studies.
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As noted above, cysLTs are well-recognized autocrine/paracrine mediators that are pertinent to eosinophils, asthma, and allergic inflammation; however, how these eicosanoids transit from their intracellular sites of synthesis for their extracellular release, which is requisite for their autocrine/paracrine functions, remains uncertain.
Should adherence to the prevailing political ideology of a given environment be requisite for addressing members of that community?
Presence of partially sulfided phase originated from rather segregated structure like Pd Pt/Al2O3 is thought to be requisite for high HDA activity.
Similarly, the GATA2 transcriptional network was discovered to be requisite for RAS oncogene-driven non-small cell lung cancer [33].
Similarly, NMDA activation appears to be requisite for gabapentin and pregabalin activity.
This implies that utilization of promoters in conserved regions might be requisite for the transcription of orfs.
Even patients who had lived alone and died at home received nursing care by their families during their last moments, suggesting that family or social supports are requisite for cancer patients to live their last moments at their own homes.
He never drinks, even though beer- and sake-soaked evenings seem to be requisites for building the kinds of information networks he commands.
As with other RTKs, ligand-induced oligomerization of Eph receptors is requisite for catalytic activation35,36.
Crowd scenes and spectacle were requisite for opera in Paris, and Verdi supplied them.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com