Sentence examples for be required for stem from inspiring English sources
These observations have led to the idea that an open chromatin structure may be required for stem cell pluripotency.
In several non-neural stem cell types and in germ cells, microRNAs have been found to be required for stem cell maintenance (for review, see [40]).
While the functions and target genes of most miRNAs are still unknown, miRNAs have been engaged in many different functions, including developmental timing, patterning and embryogenesis, differentiation and organogenesis, growth control and apoptosis and may also be required for stem cell maintenance (reviewed in [9]).
These phenotypes are associated with loss of stem cells, suggesting that Smed-set1 may be required for stem cell maintenance or proliferation.
The Piwil1 gene is a member of the Piwi gene family, which represent the first class of evolutionarily conserved genes known to be required for stem cell self-renewal and division [ 11, 12].
Since huge amount of cells are required for stem cell transplantations (Tsukamoto et al. 2013), our study suggests that HMF exposure could serve as a novel method to produce donor cells for stem cell therapy.
Our results are verified on multiple experiments and provide the first quantitative support to the hypothesis that continuity between extracellular and intracellular environments is required for stem cell fate determination.
Canonical Wnt signaling, which occurs through β-catenin bound to the HMG-box DNA binding protein Tcf/Lef, is required for stem cell self-renewal and progenitor cell proliferation in numerous vertebrate and invertebrate tissues, and de-regulation of this pathway is commonly associated with leukemia as well as epithelial cancers [33] [36].
The DKC1 complex is required for stem cell maintenance.
While CLV1 promotes stem cell differentiation, BAM receptors are required for stem cell maintenance [ 13].
For example, sufficient copper is required for stem cells to start proliferating and repairing tissues.
