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Furthermore, antibodies are expensive to produce, and are capable of inducing an immune response in the host, so "humanisation" of animal antibodies would be required for safe use of such MPIO in humans.
PCM1 and centriolar satellites are not conserved in protozoans, therefore a different mechanism may be required for safe transport of the BBSome components from their site of synthesis (as yet unidentified) to the flagellar pocket or other locations in the cell.
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The skills required from a mobile user to interact safely with his/her smartphone are different from those that are required for safe and responsible PC use.
Information on insect infestation inside stored grain bulks is required for safe grain storage.
Data acquisition and control system is required for safe and reliable operation of TWR.
An important secondary objective was to determine if radiation dosimetry prior to 90Y Zevalin administration is required for safe treatment in this patient population.
It comprises brief assessments designed to target essential functions that are required for safe driving including: vision; cognition; and motor skills.
New technologies are required for safe, site-specific and efficient control of weeds, pathogens and insects in agricultural crops and in forestry.
Assignments from the Kyoto Encyclopedia of Genes and Genomes and the Munich Information Center for Protein Sequences Functional Catalogue seem to be less conserved with sequence, probably due to a more pathway-centric view: 80% domain sequence identity is required for safe function transfer.
Since early abnormality detection with high accuracy is required for safe and reliable process operation, False Alarms Rate (FAR), Missed Detection Rate (MDR) and the detection time delay are the major factors that must be taken into consideration when developing any process monitoring scheme.
(Warning: Never look at the sun directly with telescopes or the unaided eye. Special filters are required for safe solar viewing to avoid serious eye damage). .
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