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As mentioned above, TLR6 interaction with TLR2 has been reported to be required for recognition of microbial determinants such as zymosan and Lipoteichoic acid (LTA) [31], [32].
The 3′ domain of the ZRS does not appear to be required for recognition of the Shh promoter.
The TRD and the active site reside on opposite sides of the M. RsrI monomer, but the unique dimeric configuration brings the TRD of one subunit near the active site of the other, indicating that dimerization may be required for recognition and methylation to occur.
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They found that at least 4 mol% of galactosylated cholesterol derivatives was required for recognition by receptor and 6 mol% resulted in extensive ASGPR-mediated uptake in Hep G2 cell lines.
In addition, the C-terminal glycan of CPY* (previously termed the "D-glycan") is maintained in all variants because it is required for recognition by ERAD [36].
This suggests that all three NLS-like motifs are required for recognition and the proper targeting of AtBPC6 to the nucleolus.
The lipid motif on P6 is required for recognition by TLR2 expressed on DCs and leads to a robust stimulation of T cells in vivo.
To investigate whether endocytosis was required for recognition of HCV, we tested several inhibitors that block the cellular uptake of particular structures, including viruses (Table 1).
We had previously shown that this tissue-specific peptide (70 amino acids) was required for recognition and rescue from proteasome degradation of sarcomeric substrates [18], but except for this experimental evidence, the function of this long C-terminus remained unassigned.
However, CD14 is required for recognition of 'rough LPS' through TLR4 for MyD88-independent signaling pathway.
Recent evidence has demonstrated that OBPs are required for recognition of odorants or pheromones in a number of species [ 9- 17].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com