Sentence examples for be required for persistence from inspiring English sources

Due to its role in the utilisation of intraphagosomal carbon sources, ICL has been shown to be required for persistence and virulence of M. tuberculosis in macrophage and mice [42].

A second prediction of our model is that maintenance of a pharyngeal-epidermal attachment would be required for persistence of a keyhole in embryos and for progression to a Pin phenotype in larvae.

Previously, Sass et al.24, identified a 50-gene cluster in B. cenocepacia that was highly upregulated under low oxygen culture conditions (lxa-locus) and was required for persistence under anoxic conditions.

This may explain why a minimal density of domestic ducks is required for persistence, but that their abundance does not proportionally relate to HPAI H5N1 risk.

Isocitrate lyase (ICL) and malate synthase (MS) are key glyoxylate cycle enzymes shown to be required for the persistence and virulence of Candida albicans and of Mycobacterium tuberculosis in macrophages because the up-regulation of glyoxylate genes and the corresponding enzymes could replenish C4 carbohydrates from C2 compounds in a persistent pathogen.

The conversion of isocitrate to glyoxylate is catalysed by isocitrate lyase, which has been shown to be required for the persistence of Mycobacterium tuberculosis in infected macrophages [21], [35].

What is novel here is that atypical PKC activity appears to be required for the persistence of the histone acetylation-dependent effect, possibly by suppressing histone deactylase activity.

As such, although allergy might be important in precipitating or possibly exacerbating the disorder, it has to be recognized that ongoing allergen exposure may not be required for its persistence.

Thus ISPs would not appear to be required for dissemination or persistence in the mammalian host.

One applied situation beyond the usual scenarios of invasion biology where this is particularly germane is the emergence of novel infectious diseases, where genetic adaptation to a novel host may be required for successful establishment and persistence (Holt and Hochberg 2002; Antia et al. 2003).

Alternatively, given that persistence in the host could be a potential advantage for a live attenuated vaccine, together with the evidence that ICL is required for chronic persistence of M. tuberculosis in mice [42] led us to study the persistence of the SO2 phoP mutant.