We therefore postulated that MMP inhibition might interfere with the cell-cell detachment that would be required for HOC-7 cell movement through the narrow (8 μm) transwell pores, as MMPs have been implicated in E-cadherin cleavage [ 32, 33].
If stable association with chromosomes involves entrapment of chromatin fibres inside cohesin rings and if this process involves transient hinge dissociation (Gruber et al, 2006), then the positive charge of the hinge's narrow channel cannot be required for dissociation per se, despite the fact that neutralization reduces Koff, at least in vitro.
In addition, for the TEM- and SHV-type enzymes, detailed gene sequence analysis is required for differentiating narrow-spectrum β-lactamases from ESBLs.
According to Clark & Watson [ 22], a mean inter-item correlation of 0.15 – 0.20 is desirable for scales that measure broad characteristics, while values of 0.40 0.50 are required for scales tapping narrower ones, which is the case in the present study.
Now, the gap between what network researchers can do on paper and what is required for practical demonstrations has narrowed.
The width of the tape determines the "sharpness" of the turns required to place the fibres in the prescribed direction i.e., wide tapes are used for gradual turns, while narrow tapes are required for the sharp turns associated with more complex shapes.
Interest in metals like zinc (Zn) and copper (Cu), which are required for metabolic activity in organisms, lies in the narrow "window" between their essentiality and toxicity.
Narrow-beam transmission geometry is required for μ-measurement.
Therefore, our results confirm that a narrow range of calcium concentrations is required for strong Lad1/MEKK2 interaction.
Maintaining a narrow cholesterol range within cell membranes is required for cell viability.
