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Furthermore, strong attachment forces may be required for cells migrating against a flow, such as in blood vessels.
These results indicate that increased p85 expression may contribute to enhanced activity of Akt and may be required for cells to acquire metastatic phenotype including high adhesive capacity.
As 70%to80%0% of metastatic breast cancers metastasize via the lymphatics, a particular pattern of O-linked glycans may be required for cells to migrate and/or settle in the lymph nodes.
Additionally, telomerase is up-regulated in 85% to 95% of cancer cells, which show no net loss of average telomere length, suggesting that telomere stability may be required for cells to escape replicative senescence and to proliferate indefinitely (Shay and Wright 1996; Artandi 2006).
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The SUMO pathway has been shown to be required for cell cycle progression in other organisms [59].
Therefore, down-regulation of Otud-6b expression after prolonged cytokine stimulation may be required for cell proliferation in B lymphocytes.
Cell migration and chemotaxis have been demonstrated to be required for cell collection [ 21].
Drp1 has been reported to be required for cell death in multiple circumstances.
The authors believe EXP activity may be required for cell expansion.
These data provide evidences that LRP6 may be required for cell-fate decision of osteoblast/adipocyte progenitor cells.
In Arabidopsis, RHD3 has been suggested to be required for cell wall biosynthesis and actin organization [ 55].
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