Sentence examples for be required for binding from inspiring English sources

Indeed, the four-helix bundle has been reported to be required for binding of CSN to Cul1 [25].

For example, the HVR of M5 may be required for binding to a receptor on epithelial cells.

This mutation lies within the leucine-rich domain of the extracellular part of the receptor, which has been shown to be required for binding of the TRKB ligand brain-derived neurotrophic factor (BDNF) and activation of the TRKB receptor [25], [27], [28].

Binding analysis with the biotinylated KU-174 aglycone revealed the noviose to be required for binding to Hsp90, and this confirms previously published observations.

This latter is known to be required for binding of p73 to p300 [ 62] and our model suggests that the picture is somewhat similar to that seen in p53.

Since both of these compounds lack a 1-carboxy moiety, it is reasonable to assume that the 1-carboxy substituent present in the two substrates accepted may be required for binding at the catalytic center.

For example, while nine ZFs were required for binding of BORIS isoproteins to the H19 ICR, only five were required to bind the CST probe.

Hydroxylation modification is required for binding of the von Hippel-Lindau (VHL) protein, which targets HIF-1α and HIF-2α for ubiquitination and proteasomal degradation15.

Zhang H., Kozlov G., Li X., Wu H., Gulerez I. & Gehring K. "PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3".

The full PB1-PB2 cassette is required for binding the centriolar protein Asterless as well as robust centriole targeting.

These mutants were purified and screened for binding, yielding a map of residues that are required for binding and a complementary map of residues that are not required.