Sentence examples for be required for activity from inspiring English sources

Interestingly KAI407 activity was less variable between assays than primaquine, suggesting a different metabolic pathway or mode of action, as conversion to an active metabolite does not seem to be required for activity (KAI407 is stable in the presence of liver microsomes).

Our structure activity relationship studies in this series revealed the phenol portion of the molecule to be required for activity.

One of the hallmarks of the MBOAT family of acyltransferses is the presence of two highly conserved residues, Asp/Asn (position 339 in Hhat) and His (position 379 in Hhat) within the MBOAT homology region, that have been shown to be required for activity in other MBOAT family members [24], [29], [30].

Furthermore, because expression of the hypersensitive mutant would be required for activity, we also examined mRNA.

Both systems are reversible, and in some cases, dynamic cycles of modification may be required for activity (Gill, 2004).

The presence of all four of these cysteines has been shown to be required for activity in MoeB).

(e) Under other statutory, regulatory, or administrative authorities governing the use of public lands and Indian lands, authorizations may be required for activities which do not require a permit under this part.

Our new experiment therefore supports the hypothesis that LIMK1 palmitoylation may also be required for activity-dependent functional plasticity, and may be a key link between the Cdc42 signaling and actin polymerization described by others.

The objective is to extract information about the minimal structure that is required for activity.

The results revealed that the core structure is required for activity and it should be aromatic, rigid, planar, symmetrical and conjugated for optimal activity.

However, activity was completely lost in all mutants obtained, indicating that the Y-type oxyanion hole of LipR is required for activity.