Sentence examples for be required for activation from inspiring English sources

Our studies also show that caspase activity may not be required for activation of IRF3 and NF-κB in response to intracellular dsRNA.

Moreover, the basal pro-apoptotic functions of JNK1 and c-Jun appear active despite the absence of site-specific phosphorylations known to be required for activation in response to stress.

Alternatively, SARs associated with a silent gene may be required for activation of transcription in response to stimuli (Fig. 5D).

If BAK can reside in the outer mitochondrial membrane as an inactive monomer, collision with an aBH3 would be required for activation.

For example, Thrb2 is known to be required for activation of Opn1mw and dorsal repression of Opn1sw in the mouse [52].

In addition, the SH2 domain of BCR-ABL has been shown to be required for activation of AKT through its association with the p85 subunit of PI3-kinase [35].

The products of PI3K activity are required for activation of Akt, which when constitutively activated has transforming potential.

These data suggest that ABCA1 is required for activation of scramblase activity.

These results suggest that good substrate activity and the para benzylic oxygen are required for activation by E. coli nitroreductase.

This suggests that basal PI3K activity, as seen by PDK1 phosphorylation, is required for activation of PKCs in PC3.

CASP4 cleaves and activates its own precursor protein and is required for activation of inflammasome [ 50].