Sentence examples for be reprogrammed into cells from inspiring English sources

Last year brought the sudden discovery that human adult skin cells can be reprogrammed into cells just as potent as embryonic stem cells, with no embryos harmed.

Now, Rosselló et al. have shown that cells from both invertebrate and non-mammalian vertebrate species including birds, fish and insects can be reprogrammed into cells that closely resemble iPSCs.

Recent studies showed that a variety of somatic cell types can be reprogrammed into pluripotent cells (iPS cells), closely resembling embryonic stem cells, by exposing their genome to transcription factors which activate endogenous genes involved in the maintenance of stem cells pluripotency [e.g. 1].

Remarkably, Yamanaka and colleagues [ 7, 8] observed that somatic cells can be reprogrammed into ES cell-like cells (induced pluripotent stem (iPS) cells) by the introduction of four transcription factors: Oct4, Sox2, Klf4, and Myc [ 7- 11].

On the other hand, fully differentiated cells could be reprogrammed into pluripotent cells through different approaches, including nuclear transfer, cell fusion and transcriptional-factor transduction [ 2].

TTFs were the first type of adult cells to be reprogrammed into iPS cells [1].

Furthermore, regulatory T cells can be reprogrammed into Th17 cells [35].

Since murine NSCs already express high levels of Sox2 [14]–[16], it was tested whether these cells could be reprogrammed into iPS cells by only a few critical factors.

The discovery that adult somatic stem cells can be reprogrammed into pluripotent cells is so important that, in 2012, Dr. Yamanaka was awarded with the Nobel Prize in Physiology or Medicine [ 25, 26, 28].

Regarding MSC natural origin in situ, quiescent perivascular cells presumably lose contact with blood vessels to be reprogrammed into stem/regenerative cells.

If good-quality cells can be extracted from mammoth remains – and that is a big if – they could be reprogrammed into stem cells using modern procedures.