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The maternal and early embryonic expression of mir-35 -42 suggests that its targets may be repressed at the earliest stages of embryogenesis and later released from repression.
Therefore, chronic activation of Nrf-2 may be repressed at the cost of increased cytokine production.
Flavonoid production might be repressed at the later stage by the down-regulation of CHI and F3H upon benzoic acid treatment.
We found that genes like CYCLIN D3 2, that are known to be repressed at the anthesis stage in tomato and activated at 2DPA in pollinated ovaries [ 31, 32], were actually activated at the anthesis of the parthenocarpic line.
One explanation could be that additional species-specific R-genes copies (deriving from lineage-specific WGDs), then leading to R-gene functional redundancy, may be repressed at the expressional level through miRNAs.
Thus, expression of the fimbria may contribute to transfer of the pathogen from the environment to the oral mucosa of the chicken, after which it would be repressed at the body temperature (Morales et al., 2012).
Similar(54)
Taken together, these findings suggest that most of the miRNA-mediated repression accompanies mRNA decay, although a small fraction of targets are repressed at the translational level without apparent changes in mRNA levels.
In contrast, in the homologous region of the wing ban is repressed at the dorsoventral and anteroposterior compartment boundaries (Figure 6I).
In fact, neither the zebrafish point mutation nor the zygotic null mutation of spt5 significantly de-represses hsp70-4, a gene that is repressed at the elongation level (Chen and Guo, unpublished observations, and this study).
Second, NSpt5 de-represses the transcription of hsp70-4 in zebrafish embryos and HIVLTR in cultured human cells, which are repressed at the RNAPII elongation step under non-inducible conditions.
This robust decrease of ABCA1 mRNA is consistent with the significant reduction of ABCA1 protein, suggesting that in the absence of LRP1, ABCA1 expression is repressed at the transcriptional level.
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