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Measurements of cell diameter were only carried out on cells featuring a clearly visible nucleus, to ensure the section plane was near the middle of the cell and thus measurement would be representative of cell size.
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This investigation emphasizes the importance of ENP characterization under conditions that are representative of cell culture media or physiological conditions for improved assessments of nanoparticle cytotoxicity.
Representative studies also confirmed that BrdU incorporation was representative of cell number (data not shown).
Single plane images were compared to maximum z-projections to confirm the z-projection was representative of cell appearance.
Images are representative of cell morphology during the analyses (as early as day 1 and as late as day 7 after Dox).
Fig. 6 includes histograms that were representative of cell strains with 0 25% (MDA-MB-436), 25 75% (EpH4), and 75 100% (NMuMG) reduction in S-phase after 48 hours of TGF-β1 treatment, when compared with the control cells.
It is likely that the "cancer -related cancer -related the IPA analysis are representative of categoriessses related to hypertrophy, prolifromthen, or dIPAerentianalysis opposed to areisease state; especially in such young animals (2 weeks old).
The fluorescence on the Y-axis is representative of cells undergoing cell death.
Importantly, immunohistochemical studies indicate that disaggregated SRT cells are representative of cells within the synovium.
Of the remaining annotations, there are representatives of cell growth and metabolism (Interleukin enhancer binding factor, phosphoserine aminotransferase, D-3-phosphoglycerate dehydrogenase), cell proliferation (Macrophage stimulating 1 hepatocyte growth factor-like), and cell signaling (Inositol monophosphatase).
Most mathematical models of biochemical pathways consider either signalling events that take place within a single cell in isolation, or an 'average' cell which is considered to be representative of a cell population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com