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The in vitro study is conducted to determine that the neurogenesis regulating effect could be replicated in cell culture system.
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It also remains to be seen if the new chromosomes will be replicated in cells inside animals and humans, says Savio Woo, who directs the Gene Therapy Institute at the Mt . Sinai School of Medicinein New York City.
Vector DNAs containing a site-specific γ-OH-PdG were replicated in cells either following stress induction or with no stress.
This represents an important pathophysiological context that cannot be replicated in immortalised cell cultures.
Amplification increases the amount of DNA that has to be replicated in every cell cycle, whereas errors in nick repair can cause chromosome breaks.
Once endocytosed, HCVs can be replicated in liver cells and bud off, continue to invade other liver cells, and subsequently cause liver cancer.
The documented reduction in GM-CSF production by Teff cells exposed to IL-12 or IL-27 24, could be replicated in iTreg cells.
This phenotype can be replicated in a HeLa cell culture model by siRNA knockdown of AP-5 ζ.
Only about half of all PICH-positive fibers were BrdU positive, consistent with the fact that not all centromere DNA will be replicated in asynchronously growing cells during a 10-h labeling.
(i) Initially the incoming gene(s) must be replicated in the original recipient cell and its immediate progeny.
Remarkably, it was found that they utilize distinct cultured cell lines for in vitro virus propagation, since PEDV could not be replicated in swine testis (ST) cells expressing native porcine APN (pAPN), which are highly susceptible to TGEV.
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