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In particular, we ask the question, what level of recombination in human mtDNA might we need before it can be reliably detected with the currently available recombination detection tools?
Nonetheless, this is a good example that even primitive, linear straight-forward influences can be reliably detected with this method.
This can be reliably detected with ultramicroscopy.
This demonstrates that blood vessel alterations can be reliably detected with our setup.
We have demonstrated that an event related motor gamma band peak can be reliably detected with as few as eight subjects and a protocol lasting under 2 min.
Indeed, in a previous study, TPC2 overexpression was required before NAADP responses could be reliably detected with the cytosolic indicator fluo-3 [ 15].
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Scans were reliably detected with as few as 4 IPs scanned per attempt, and in no case did a single scan of 5 or more scanned IPs escape detection.
Rare copy-number variants have been found to explain nearly 3% of individuals with IGE; however, it remains unclear whether variants with moderate effect size and frequencies below what are reliably detected with genome-wide association studies contribute significantly to disease risk.
Using this imaging method, nerve injury was reliably detected with strong lesion contrast even before the manifestation of symptomatic disease in asymptomatic carriers with confirmed disease-causing mutations of the TTR gene (Val30Met, Leu58His or Tyr69His).
Simulations show that the fit method can indeed robustly discriminate between the effects of different model parameters on the shape of the sucrose response, that is, changes in one model parameter are reliably detected with the other model parameters being invariant.
Melting curve studies with complementary oligonucleotides predicted that asparagine at codon 138 would be reliably detected along with L141 and F141 in all homozygous and heterozygous allele combinations (table 4).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com